Pronounced: Neh-frah-tik sin-drome
by Laurie LaRusso, MS, ELS
Nephrotic syndrome is a group of changes affecting the kidneys. These may involve:
Tiny tubules inside the kidneys filter wastes from blood and make urine. If they aren’t working well, wastes and fluids build up in the body.
Causes are from kidney related health problems such as:
Causes from other health problems that harm the kidneys such as:
Your risk is higher if you have:
If you have problems, you may notice:
The doctor will ask about your symptoms and health history. Your answers and a physical exam may point to nephrotic syndrome. You may also have:
You will be referred to a specialist for care.
Care depends on the cause. In some people, nephrotic syndrome goes away on its own.
If needed, care focuses on keeping the kidneys working and lowering the chances of further injury. It may involve:
There are no steps to prevent nephrotic syndrome. To lower your chances of kidney problems:
National Institute of Diabetes and Digestive and Kidney Diseases
National Kidney Foundation
The Kidney Foundation of Canada
Nephrotic syndrome. National Kidney Foundation website. Available at: https://www.kidney.org/atoz/content/nephrotic. Accessed June 7, 2018.
Nephrotic syndrome in adults. EBSCO DynaMed Plus website. Available at: http://www.dynamed... . Updated March 21, 2016. Accessed June 7, 2018.
Nephrotic syndrome in adults. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/kidney-disease/nephrotic-syndrome-adults. Updated February 2014. Accessed June 7, 2018.
Overview of nephrotic syndrome. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/genitourinary-disorders/glomerular-disorders/overview-of-nephrotic-syndrome#v1056004. Updated January 2018. Accessed June 7, 2018.
Last reviewed May 2018 by EBSCO Medical Review Board Adrienne Carmack, MD
Last Updated: 6/7/2018