Coaptite Injection

Coaptite Injection

(Injection, Coaptite)


Coaptite is a gel-like substance that is used as a bulking agent. It is injected around the sphincter where the urethra and bladder meet. Sphincter muscles control the release of urine from the bladder. The substance supports the urethra, decreasing incontinence.

Reasons for Procedure    TOP

This procedure is for women who have stress urinary incontinence. This is the leakage of urine caused by weakening of the muscles around the bladder and pelvis.

Muscles Involved in Incontinence in Women

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Copyright © Nucleus Medical Media, Inc.

Possible Complications    TOP

If you are planning to have a coaptite injection, your doctor will review a list of possible complications which may include:

  • Trouble passing urine due to urethra swelling
  • Blood in urine
  • Painful urination
  • Urinary tract infection
  • Feeling the urge to urinate
  • Frequent urination
  • Continued incontinence
  • Bleeding
  • Damage to the urethra
  • Reaction to anesthesia

You should avoid this procedure if you have a history of:

  • Urinary tract infections
  • Current irritation of your bladder or urethra

Be sure to discuss these risks with your doctor before the injection.

What to Expect    TOP

Prior to Procedure

Your doctor may do the following:

  • Physical exam, blood and urine tests, and imaging tests
  • Discuss with you the type of anesthesia that will be used and the potential risks

Talk to your doctor about your medications. You may be asked to stop taking some medications up to one week before the procedure.

Other things to keep in mind before the procedure:

  • Arrange for a ride home from the hospital.
  • If instructed by your doctor, do not eat or drink for 8 hours before the procedure.


This procedure can be done under local, spinal, or general anesthesia. It will block any pain. Sedation may also be used to ease anxiety.

Description of Procedure    TOP

An IV will be placed in your arm. It will deliver fluids and medications directly into your bloodstream. A special jelly or fluid may be placed into your urethra to numb the area. If you are having spinal anesthesia, it will be injected into the spine. General anesthesia will be given through an IV.

A tiny camera will be inserted into your urethra. This will allow the doctor to see the bladder. The coaptite substance will be passed through the scope. It will be injected into the urethra wall near the bladder. The procedure will be repeated on the other side of the urethra. The gel will create a bulge just under the bladder.

Immediately After Procedure    TOP

You will be monitored as the anesthesia wears off.

How Long Will It Take?    TOP

The procedure usually takes 15-30 minutes.

How Much Will It Hurt?    TOP

Anesthesia prevents pain during the procedure. Ask your doctor about medication to help with pain after the injection.

Post-procedure Care    TOP

At the Care Center

After the procedure, the hospital staff may provide the following care:

  • Monitor you while you recover from the anesthesia and/or sedation
  • Help you to eat and move around again
  • Give you pain medication

You will not need to stay overnight.

At Home

When you return home, do the following to help ensure a smooth recovery:

  • Avoid difficult activity and heavy lifting.
  • Do not have sex until your doctor says it is safe to do so.
  • Be sure to follow your doctor’s instructions.

Call Your Doctor    TOP

After arriving home, contact your doctor if you have any of the following:

  • Increased pressure or pain
  • Inability to urinate
  • Changes in frequency, odor, appearance, or volume of urine
  • Signs of infection, including fever or chills
  • Blood in urine
  • Painful urination or a burning sensation
  • Leaking urine

In case of an emergency, call for emergency medical services right away.


National Institute of Diabetes and Digestive and Kidney Diseases
Urology Care Foundation


Canadian Urological Association


Coaptite. United States Food and Drug Administration website. Available at:
...(Click grey area to select URL)
Updated September 4, 2013. Accessed November 18, 2015.
Incontinence. American Association of Family Physicians website. Available at:
...(Click grey area to select URL)
Updated April 2014. Accessed November 18, 2015.
Incontinence. Urology Care Foundation website. Available at:
...(Click grey area to select URL)
Accessed November 18, 2015.
Last reviewed November 2015 by Adrienne Carmack, MD
Last Updated: 12/20/2014

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